Figure 1.   (a) Crystal structure of the full‐length human low‐molecular‐weight phosphotyrosine phosphatase (LMPTP‐A), PDB code 5pnt;   (b) Predicted structure of the shortened alternatively spliced variant LMPTP‐C). The region deleted by the alternative splicing event is colored gray; the region of local structural change in LMPTP‐C is colored black.

Figure 2. Sequence alignment of full‐length human low‐molecular‐weight phosphotyrosine phosphatase (LMPTP‐A) and its truncated variant (LMPTP‐C) reported by the fold‐recognition method PHYRE, used to model the structure of the latter. ss = secondary structure of LMPTP‐A derived from crystal structure. The cylinders represent α‐helices; the arrows represent β‐strands.