Figure 1. Recent structures of protein–DNA complexes determined by NMR spectroscopy.

Figure 2. Structural and dynamic transitions in protein–DNA recognition. (a) Pathway of binding of the free LacR DBD, first to nonspecific DNA and then to the operator site. (b) Concomitant changes in dynamics probed via relaxation exchange contributions. (c) Effect of the S62F mutation on the dynamics in the CAP–DNA complex [ 3, 4].

Figure 3. Mapping of DNA‐binding interfaces for the heterodimeric complex of the nucleotide excision repair proteins ERCC1 and XPF (a), and the nucleoid‐associated protein H‐NS (b).

Figure 4. Regions with protein–DNA NOEs in one‐dimensional and – two‐dimensional NOE spectra in D ₂O.

Figure 5. Model of the complex of the BRCT domain of replication factor C with DNA, obtained by the docking program HADDOCK.

Figure 6. Influence of salt on the affinity of nonspecific (dashed line) and specific (solid line) protein–DNA binding for a short (black) and long DNA fragment (red).