Introducing Chirality at Phosphorus Atoms: An Update on the Recent Synthetic Strategies for the Preparation of Optically Pure P-Stereogenic Molecules

Introducing Chirality at Phosphorus Atoms: An Update on the Recent Synthetic Strategies for the Preparation of Optically Pure P-Stereogenic Molecules

This review presents the recent developments in the preparation of P-stereogenic molecules via several synthetic approaches: a) chiral auxiliary bound to the P atom, b) chiral stoichiometric reagent, c) catalytic enantioselective reactions or d) semi-preparative chiral separation.

[Minireview]
Dr. Sébastien Lemouzy, Dr. Laurent Giordano, Dr. Damien Hérault, Prof. Gérard Buono
European Journal of Organic Chemistry, https://doi.org/10.1002/ejoc.202000406. Read article.

Diethylsilane as a Powerful Reagent in Au Nanoparticle-Catalyzed Reductive Transformations

Diethylsilane as a Powerful Reagent in Au Nanoparticle-Catalyzed Reductive Transformations

Diethylsilane exhibits remarkable reactivity relative to typical hydrosilanes in the reduction of carbonyl compounds, imines, and amides catalyzed by Au nanoparticles.

[Full Papers]
Anastasia Louka, Dr. Marios Kidonakis, Iakovos Saridakis, Elisavet-Maria Zantioti-Chatzouda, Dr. Manolis Stratakis
European Journal of Organic Chemistry, https://doi.org/10.1002/ejoc.202000483. Read article.

Systematic Evaluation of Imine-Reducing Enzymes: Common Principles in Imine Reductases, β-Hydroxy Acid Dehydrogenases, and Short-Chain Dehydrogenases/ Reductases

Systematic Evaluation of Imine-Reducing Enzymes: Common Principles in Imine Reductases, β-Hydroxy Acid Dehydrogenases, and Short-Chain Dehydrogenases/ Reductases

The enzymatic, asymmetric reduction of imines to chiral amines is a valuable biocatalytic approach owing to the high enantioselectivity of the reductases. Imine reductases, short-chain dehydrogenases/reductases, and β-hydroxy acid dehydrogenases are known to catalyze this reaction. Our systematic evaluation of the structures and substrate-binding sites of the three enzyme families has revealed four common principles for enzymatic imine reduction.

[Full Papers]
Peter Stockinger, Sebastian Roth, Prof. Dr. Michael Müller, Prof. Dr. Jürgen Pleiss
ChemBioChem, https://doi.org/10.1002/cbic.202000213. Read article.

Synthesis of Chlorinated, Heteroatom-Rich and Differently Fused Tricyclic β-Lactams by Cu(I)-Catalyzed Halogen Atom Transfer Radical Cyclization

Synthesis of Chlorinated, Heteroatom-Rich and Differently Fused Tricyclic β-Lactams by Cu(I)-Catalyzed Halogen Atom Transfer Radical Cyclization

The present work has described an optimized synthetic methodology to prepare a library of various tricyclic β-lactams which are heteroatom rich and differently fused. The method has been diversified by using a wider substrate scope. The moieties synthesized may serve as good precursors for biological and computational studies. The synthetic strategy developed in this paper for the organic synthesis of several compounds may provide an important synthetic pathway for the development of several new pharmacological entities.

[Full Papers]
Dr. Nisha Dawra, Prof. Ram N. Ram, Sujeet K. Thakur
ChemistrySelect 2020, 5, 6204. Read article.

High-Throughput Synthesis and Screening of Functional Coacervates Using Microfluidics

High-Throughput Synthesis and Screening of Functional Coacervates Using Microfluidics

Open reaction centers : Droplet-based microfluidics allows the high-throughput synthesis and screening of populations of micron-sized coacervates with an unprecedented accuracy. The study of partition coefficients and sequestered reaction rates in these minimal synthetic organelles provides insights in the role of sub-compartmentalisation in regulating out-of-equilibrium behaviours in biological systems.

[Full Papers]
Dr. Thomas Beneyton, Celina Love, Dr. Mathias Girault, Dr. T.-Y. Dora Tang, Prof. Jean-Christophe Baret
ChemSystemsChem, https://doi.org/10.1002/syst.202000022. Read article.

Multivalent and Multifunctional Calixarenes in Bionanotechnology

Multivalent and Multifunctional Calixarenes in Bionanotechnology

In the 70's, when Calixarenes started to appear in the literature, no one would have bet even a cent on the future of these strange cyclic oligomers. Fifty years later, a series of appealing features make calixarene a versatile scaffold for the design of ligands with applications ranging from nuclear waste technology to bionanotechnology and nanomedicine.

[Minireview]
Prof. Laura Baldini, Prof. Alessandro Casnati, Prof. Francesco Sansone
European Journal of Organic Chemistry, https://doi.org/10.1002/ejoc.202000255. Read article.

Multicomponent Synthesis of Sulfones and Sulfides from Triarylbismuthines and Sodium Metabisulfite in Deep Eutectic Solvents

Multicomponent Synthesis of Sulfones and Sulfides from Triarylbismuthines and Sodium Metabisulfite in Deep Eutectic Solvents

A novel and catalyst-free methodology for the multicomponent synthesis of a broad range of sulfones, disulfides, and sulfides from non-toxic triarylbismuthines (Ar3Bi) and sodium metabisulfite (Na2S2O5) in deep eutectic solvents (DESs), has been described for the first time.

[Full Papers]
Beatriz Saavedra, Xavier Marset, Dr. Gabriela Guillena, Dr. Diego J. Ramón
European Journal of Organic Chemistry, https://doi.org/10.1002/ejoc.202000425. Read article.

Enhancement of Functional Properties of Liquid Electrolytes for Lithium-Ion Batteries by Addition of Pyrrolidinium-Based Ionic Liquids with Long Alkyl-Chains

Enhancement of Functional Properties of Liquid Electrolytes for Lithium-Ion Batteries by Addition of Pyrrolidinium-Based Ionic Liquids with Long Alkyl-Chains

The pursuit of electrolytes : Innovative non-aqueous electrolytes for Li-ion batteries with superior safety features compared to commercial products are formulated and characterized: here, the unique physico-chemical properties of ionic liquids to push the capability of liquid electrolytes beyond the state-of-the-art are exploited.

[Articles]
Arcangelo Celeste, Dr. Laura Silvestri, Dr. Marco Agostini, Matthew Sadd, Stefano Palumbo, Dr. Jaya Kumar Panda, Dr. Aleksandar Matic, Dr. Vittorio Pellegrini, Dr. Sergio Brutti
Batteries & Supercaps, https://doi.org/10.1002/batt.202000070. Read article.

Biocatalytic Alkylation Cascades: Recent Advances and Future Opportunities for Late-Stage Functionalization

Biocatalytic Alkylation Cascades: Recent Advances and Future Opportunities for Late-Stage Functionalization

Enzymatic approaches that transfer a methyl group from S -adenosyl methionine to a target substrate are powerful methods used by nature to alter biological function. These processes are now being tailored for late-stage alkylation of small molecules and bio-macromolecules. This Concept article summarizes recent approaches and challenges towards establishing a generalized platform for biocatalytic alkylation.

[Concepts]
Dr. Iain J. W. McKean, Prof. Paul A. Hoskisson, Prof. Glenn A. Burley
ChemBioChem, https://doi.org/10.1002/cbic.202000187. Read article.

Cobalt-Catalyzed Oxidative C−H Activation: Strategies and Concepts

Cobalt-Catalyzed Oxidative C−H Activation: Strategies and Concepts

Metal-catalyzed C−H activation has emerged as an increasingly powerful tool for molecular synthesis, with major advances achieved by using Earth-abundant cobalt catalysts. Recent momentum was gained by oxidative C−H transformations, prominently featuring aerobic and electrochemical approaches. Herein, the findings in this topical area of sustainable synthesis are summarized and critically discussed.

[Reviews]
Prof. Dr. Ruhuai Mei, Uttam Dhawa, Dr. Ramesh C. Samanta, Prof. Dr. Wenbo Ma, Dr. Joanna Wencel-Delord, Prof. Dr. Lutz Ackermann
ChemSusChem, https://doi.org/10.1002/cssc.202000024. Read article.

Photocatalytic Conversion of Lignin into Chemicals and Fuels

Photocatalytic Conversion of Lignin into Chemicals and Fuels

The lighter side of lignin : Photocatalytic depolymerization of lignin and its oxidative, reductive and redox-neutral mechanisms have attracted much attention. This Review concerns the development and application of various homogeneous and heterogeneous photocatalysts for lignin depolymerization. In addition, other factors that affect the reaction, including the reactor, solvent, and atmosphere, are also introduced.

[Reviews]
Zhiyu Xiang, Wanying Han, Prof. Jin Deng, Prof. Wanbin Zhu, Prof. Ying Zhang, Prof. Hongliang Wang
ChemSusChem, https://doi.org/10.1002/cssc.202000601. Read article.

Supramolecular Construction of a [16]-Imidazolium Cage via a Quadruple [2+2] Photocycloaddition and Its Selective Fluorescent Recognition of Pyranine (HPTS)

Supramolecular Construction of a [16]-Imidazolium Cage via a Quadruple [2+2] Photocycloaddition and Its Selective Fluorescent Recognition of Pyranine (HPTS)

Fluorescent recognition : A tetragonal hexadecakisimidazolium cage, achieved through a metal-carbene-directed quadruple photochemical [2+2] cyclization reaction, demonstrated high efficiency for the selective “turn-off” fluorescent recognition of HPTS (8-hydroxy-1,3,6-pyrene trisulfonate).

[Communications]
Kai Hua, Dr. Yuan-Yuan An, Prof. Dr. Yao-Yu Wang, Prof. Dr. Ying-Feng Han
Chemistry – A European Journal, https://doi.org/10.1002/chem.202001138. Read article.

Transition Metal Phosphide-Based Materials for Efficient Electrochemical Hydrogen Evolution: A Critical Review

Transition Metal Phosphide-Based Materials for Efficient Electrochemical Hydrogen Evolution: A Critical Review

Transitioning to hydrogen : In this Review, up-to-date progress of transition metal phosphide (TMP)-based hydrogen evolution reaction (HER) electrocatalysts is summarized. Various synthesis strategies and the HER reaction mechanisms of TMP-based catalysts are briefly discussed. In addition, multiscale approaches with respect to electronic structure, hybrids, microstructure, and working electrode interface are discussed for promoting HER performances.

[Reviews]
Chen-Chen Weng, Jin-Tao Ren, Prof. Zhong-Yong Yuan
ChemSusChem, https://doi.org/10.1002/cssc.202000416. Read article.

Research Progress in Lignin-Based Slow/Controlled Release Fertilizer

Research Progress in Lignin-Based Slow/Controlled Release Fertilizer

Fertile waste : Research progress in lignin-based slow/controlled release fertilizers is summarized in this Review by considering chemical (ammoxidation, Mannich reaction, and other chemical modifications), coating (without or with chemical modification), and chelation modifications.

[Minireviews]
Jing Chen, Prof. Dr. Xiaolin Fan, Dr. Lidan Zhang, Xiaojuan Chen, Prof. Dr. Shaolong Sun, Prof. Dr. Run-Cang Sun
ChemSusChem, https://doi.org/10.1002/cssc.202000455. Read article.

Tunable Thiolate Coordination Networks on Metal Surfaces

Tunable Thiolate Coordination Networks on Metal Surfaces

The structure of thiolate coordination networks on the Cu(111) surface is controlled by adjusting the surface temperature of the deposition.

[Communications]
Dr. Xiangzhi Meng, Elena Kolodzeiski, Xing Huang, Alexander Timmer, Bertram Schulze Lammers, Dr. Hong-Ying Gao, Dr. Harry Mönig, Lacheng Liu, Dr. Wei Xu, Dr. Saeed Amirjalayer, Prof. Daoben Zhu, Prof. Harald Fuchs
ChemNanoMat, https://doi.org/10.1002/cnma.202000267. Read article.

Robust Guanidine Metal Catalysts for the Ring-Opening Polymerization of Lactide under Industrially Relevant Conditions

Robust Guanidine Metal Catalysts for the Ring-Opening Polymerization of Lactide under Industrially Relevant Conditions

Faster and better : This Minireview presents the latest and most rapid robust catalysts for the ring-opening polymerization of lactide under industrial conditions. The focus is on the search for a substitute for the currently most commonly used and toxic catalyst Sn(Oct)2 in industry. Numerous ROP-active guanidine metal complexes are presented, and their activity is compared by analyzing the rate constants of the polymerization.

[Minireviews]
Dr. Pascal M. Schäfer, Prof. Dr. Sonja Herres-Pawlis
ChemPlusChem 2020, 85, 1044. Read article.

Circularly Polarized Luminescence from Bischromophoric Cyanostilbene-Derived Homochiral Nanostructures in Solution

Circularly Polarized Luminescence from Bischromophoric Cyanostilbene-Derived Homochiral Nanostructures in Solution

Circularly polarized luminescence (CPL)-active self-assembled bischromophoric cyanostilbenes with a remarkable luminescence dissymmetry factor (glum) have been realized in the solution state. Control over morphology can be achieved by fine-tuning the concentration of the solution. Strong homochiral recognition of trans -1,2-bis(amido)cyclohexane enables formation of organic conglomerates in the solution, thus resulting in tunable CPL in co-assembled enantiomeric solution.

[Communications]
Souvik Sarkar, Dr. Bhawani Narayan, Prof. Dr. Subi J. George
ChemNanoMat, https://doi.org/10.1002/cnma.202000275. Read article.

Ni2P-Modified Ta3N5 and TaON for Photocatalytic Nitrate Reduction

Ni2P-Modified Ta3N5 and TaON for Photocatalytic Nitrate Reduction

Photocatalytic reduction of NO3 over visible-light-active Ni2P-modified Ta3N5 or TaON photocatalysts is reported.

[Full Papers]
Lin Wei, Marquix A. S. Adamson, Prof. Dr. Javier Vela
ChemNanoMat, https://doi.org/10.1002/cnma.202000174. Read article.

Functional Covalent Triazine Frameworks-Based Quasi-Solid-State Electrolyte Used to Enhance Lithium Metal Battery Safety

Functional Covalent Triazine Frameworks-Based Quasi-Solid-State Electrolyte Used to Enhance Lithium Metal Battery Safety

Say no to dendrites : A new class of quasi-solid-state electrolyte (QSSE) consisting of ionic liquid functional covalent triazine-based frameworks (IL-fCTF) and lithium salt ionic liquid (LIL) is formed by simple mechanical mixing. The fabricated QSSE has excellent mechanical stability derived from its robust CTF skeleton and a high ionic conductivity that originates from absorbed LIL.

[Articles]
Dr. Qing Xuan Shi, Xin Guan, Hui Jie Pei, Chen Chang, Hao Qu, Prof. Xiao Lin Xie, Yun Sheng Ye
Batteries & Supercaps, https://doi.org/10.1002/batt.202000069. Read article.

Effect of Regiochemistry and Methylation on the Anticancer Activity of a Ferrocene-Containing Organometallic Nucleoside Analogue

Effect of Regiochemistry and Methylation on the Anticancer Activity of a Ferrocene-Containing Organometallic Nucleoside Analogue

Stay on the same side : An anticancer 1,2-disubstituted ferronucleoside (R=H) retains micromolar toxicity in bone cancer cell lines when methylated in up to two positions but activity is lost for its 1,1′ regioisomer, which otherwise has similar redox properties and the same linker stereochemistry.

[Full Papers]
Media K. Ismail, Dr. Zahra Khan, Marium Rana, Dr. Sarah L. Horswell, Dr. Louise Male, Dr. Huy V. Nguyen, Dr. Alessio Perotti, Dr. Isolda Romero-Canelón, Edward A. Wilkinson, Dr. Nikolas J. Hodges, Prof. James H. R. Tucker
ChemBioChem, https://doi.org/10.1002/cbic.202000124. Read article.

Metallic Nanoparticle-Enabled Sensing of a Drug-of-Abuse: An Attempt at Forensic Application

Metallic Nanoparticle-Enabled Sensing of a Drug-of-Abuse: An Attempt at Forensic Application

GHB analysis in forensic sample matrices : The date-rape drug γ-hydroxybutyric acid (GHB) can be detected after a highly specific enzymatic reaction that generates NADH. NADH helps to reduce gold(III) species to form pinkish AuNPs that can be seen even with the naked eye in a variety of spiked drinks. The strategy can also be used to analyze GHB in complicated biological samples.

[Full Papers]
Ming Hu, Qinyu Han, Prof. Dr. Bengang Xing
ChemBioChem, https://doi.org/10.1002/cbic.202000157. Read article.

Controlled Supramolecular Polymerization of d8 Metal Complexes through Pathway Complexity and Seeded Growth

Controlled Supramolecular Polymerization of d8 Metal Complexes through Pathway Complexity and Seeded Growth

In this Minireview, recent examples are presented of d8 metal complexes that exhibit competing kinetic and thermodynamic pathways, a property that has been exploited to control the length of supramolecular polymers via the seed-induced living approach. Kinetically controlled products in these systems can be achieved by modulation of various experimental conditions (solvent composition, temperature, concentration, etc.) as well as by molecular design. The understanding gained from these studies may pave the way to sophisticated metallosupramolecular assemblies with tunable size and shape and exciting optical and electronic properties.

[Minireviews]
Dr. Goutam Ghosh, Dr. Tanwistha Ghosh, Prof. Dr. Gustavo Fernández
ChemPlusChem 2020, 85, 1022. Read article.

HI/DMSO-Catalyzed Cyclization of Aryl(sulfo)acylhydrazones with Sulfur

HI/DMSO-Catalyzed Cyclization of Aryl(sulfo)acylhydrazones with Sulfur

HI/DMSO-Catalyzed cyclization of aryl(sulfo)acylhydrazones with sulfur was developed, and various 4-aryl-1,2,3-thiadiazoles were obtained with moderate to excellent yields. Notably, DMSO, the environmentally friendly reagent, was employed as dual solvent and oxidant without any external inorganic or hazardous organic oxidants.

[Full Papers]
Jun Zhang, Weiwei Li, Dr. Yan Liu, Prof. Ping Liu
ChemistrySelect 2020, 5, 5497. Read article.

High Cycling Stability for Solid-State Li Metal Batteries via Regulating Solvation Effect in Poly(Vinylidene Fluoride)-Based Electrolytes

High Cycling Stability for Solid-State Li Metal Batteries via Regulating Solvation Effect in Poly(Vinylidene Fluoride)-Based Electrolytes

Non-negligible effect : The solvation effect caused by a small amount of residual DMF bound in PVDF-based electrolytes plays an important role in the ionic conduction, the electrolyte-electrode interfacial reaction, and thus cell performance. By regulating the solvation effect, the PVDF-based electrolytes show both high ionic conductivity and high interface stability and finally deliver excellent cycling performance in full cell.

[Communications]
Xue Zhang, Jian Han, Xiangfu Niu, Chengzhou Xin, Chuanjiao Xue, Shuo Wang, Prof. Yang Shen, Prof. Liang Zhang, Prof. Liangliang Li, Prof. Ce-Wen Nan
Batteries & Supercaps, https://doi.org/10.1002/batt.202000081. Read article.

Tailored Silicon/Carbon Compounds for Printed Li-Ion Anodes

Tailored Silicon/Carbon Compounds for Printed Li-Ion Anodes

Powering printed electronics : Nano silicon (Si) is an attractive candidate for lithium-ion batteries (LIBs) in comparison to graphite, since it delivers 10 times more capacity than commercially available graphite electrodes. The carbon coated Si composites are demonstrated as a potential anode material for LIBs and possess stable capacity for >100 cycles. Our study found out that full cells fabricated with printed Si coated carbon composite anode are able to power the printed transistor circuitry.

[Articles]
Parvathy Anitha Sukkurji, Dr. Ibrahim Issac, Surya Abhishek Singaraju, Dr. Leonardo Velasco, Prof. Jasmin Aghassi Hagmann, Prof. Wolfgang Bessler, Prof. Horst Hahn, Dr. Miriam Botros, Dr. Ben Breitung
Batteries & Supercaps, https://doi.org/10.1002/batt.202000052. Read article.

Recent Developments in Electrochemistry-Mass Spectrometry

Recent Developments in Electrochemistry-Mass Spectrometry

Joined at the hip : This Review gives an overview of recent developments in the hyphenation of electrochemistry and mass spectrometry. Important historical developments and aspects of terminology are discussed. An introduction to different experimental approaches such as differential electrochemical mass spectrometry, hyphenation of electrochemical flow cells to mass spectrometry and electrochemistry coupled to capillary electrophoresis or high-performance liquid chromatography and mass spectrometry is given. Scientific reports from 2017 to 2020 are shortly summarized.

[Reviews]
Thomas Herl, Prof. Frank-Michael Matysik
ChemElectroChem, https://doi.org/10.1002/celc.202000442. Read article.

Direct Synthesis of Ammonia from N2 and H2O on Different Iron Species Supported on Carbon Nanotubes using a Gas-Phase Electrocatalytic Flow Reactor

Direct Synthesis of Ammonia from N2 and H2O on Different Iron Species Supported on Carbon Nanotubes using a Gas-Phase Electrocatalytic Flow Reactor

Go with the flow : Small (<1-2 nm) iron-oxide nanoparticles strongly interacting with carbon nanotubes are the active species responsible for the N2 reduction reaction (NRR) at low applied potential (−0.5 V vs RHE).

[Articles]
Dr. Shiming Chen, Prof. Siglinda Perathoner, Prof. Claudio Ampelli, Dr. Hua Wei, Dr. Salvatore Abate, Prof. Bingsen Zhang, Prof. Gabriele Centi
ChemElectroChem, https://doi.org/10.1002/celc.202000514. Read article.

Impact of H2 and Consecutive H2O2 Exposures on the Oxidative Dissolution of (U1-x Gdx )O2 Pellets Under Deep Repository Conditions for Spent Nuclear Fuel

Impact of H2 and Consecutive H2O2 Exposures on the Oxidative Dissolution of (U1-x Gdx )O2 Pellets Under Deep Repository Conditions for Spent Nuclear Fuel

With increasing H2O2 exposure the dissolution yield of Gd-doped UO2 decreases. This indicates a change in the redox reactivity of Gd-doped UO2 upon the exposure to H2O2. An inhibiting effect of H2 on the oxidative dissolution of Gd-doped UO2 could not be observed.

[Full Papers]
Dr. Annika Carolin Maier, Dr. Alexandre Barreiro Fidalgo, Prof. Dr. Mats Jonsson
European Journal of Inorganic Chemistry 2020, 1946. Read article.

Synthesis and Anti-Proliferative Activity of a Triazole-Fused Thymidine Analogue

Synthesis and Anti-Proliferative Activity of a Triazole-Fused Thymidine Analogue

Two analogues of thymidine containing the triazole moiety were synthesized through an intramolecular 1,3-dipolar cycloaddition reaction. Experimental and docking studies showed that one of these nucleoside analogues exhibited dose dependent cytotoxicity against glioblastoma and breast cancer cells.

[Communications]
Atikur Rahman, Priyanka Sharma, Navneet Kaur, Dr. Asifkhan Shanavas, Dr. Prakash P. Neelakandan
ChemistrySelect 2020, 5, 5473. Read article.

Design of Drug-Like Protein-Protein Interaction Stabilizers Guided By Chelation-Controlled Bioactive Conformation Stabilization

Design of Drug-Like Protein-Protein Interaction Stabilizers Guided By Chelation-Controlled Bioactive Conformation Stabilization

No PAINS, no gain ! Chelation is associated with pan-assay interference compounds (PAINS) but can also lead to true potency gains and be exploited to guide medicinal chemistry optimization. Bivalent metal ions increased the potency of a marginally active 14-3-3 PPI stabilizer up to 100-fold via stabilization of the bioactive ligand conformation. Mimicry of this by intramolecular H-bonds led to the first potent, drug-like 14-3-3 PPI stabilizers (see figure).

[Full Papers]
Francesco Bosica, Dr. Sebastian A. Andrei, Dr. João Filipe Neves, Dr. Peter Brandt, Dr. Anders Gunnarsson, Dr. Isabelle Landrieu, Prof. Christian Ottmann, Dr. Gavin O'Mahony
Chemistry – A European Journal 2020, 26, 7131. Read article.

Gold-Catalyzed [3+2] Carbocycloaddition Reaction of Pinacol Alkenylboronates: Stereospecific Synthesis of Boryl-Functionalized Cyclopentene Derivatives

Gold-Catalyzed [3+2] Carbocycloaddition Reaction of Pinacol Alkenylboronates: Stereospecific Synthesis of Boryl-Functionalized Cyclopentene Derivatives

Going for gold ! An efficient gold-catalyzed [3+2] cycloaddition of vinyldiazoacetates and vinylboronates has been developed. The boryl-substituted cyclopentene derivatives are obtained with complete regio- and stereoselectivity and can easily be converted into densely substituted cyclopentene derivatives by well-established methodologies (see scheme).

[Communications]
Kota Yamamoto, Dr. Enol López, Dr. Pablo Barrio, Dr. Javier Borge, Prof. Luis A. López
Chemistry – A European Journal 2020, 26, 6999. Read article.

Small Gold(I) and Gold(I)-Silver(I) Clusters by C−Si Auration

Small Gold(I) and Gold(I)-Silver(I) Clusters by C−Si Auration

With gold and silver : Auration of o -trimethylsilyl arylphosphines leads to the formation of gold and gold-silver clusters with ortho -metalated phosphines displaying 3c-2e Au−C−M bonds (M=Au/Ag). The activity of these small gold clusters has been studied in typical AuI-catalyzed reactions of enynes.

[Full Papers]
Dr. Xiao-Li Pei, Dr. Ana Pereira, Dr. Ekaterina S. Smirnova, Prof. Antonio M. Echavarren
Chemistry – A European Journal, https://doi.org/10.1002/chem.202001509. Read article.

Interactions and Transport in Highly Concentrated LiTFSI-based Electrolytes

Interactions and Transport in Highly Concentrated LiTFSI-based Electrolytes

Batteries : To understand how ionic transport in Li-ion battery electrolytes is affected by very high salt concentrations, the properties of nine model electrolytes were studied. The electrolytes were based on the common LiTFSI salt in concentrations ranging from ca. 0.7 to 7 mol/kg in solvents spanning a range of viscosities and permittivities. The ionic diffusion, ionic conductivity, and ionic association all change and impact on the rate capabilities of Li-ion battery cells.

[Articles]
Dr. Viktor Nilsson, Dr. Diana Bernin, Prof. Daniel Brandell, Prof. Kristina Edström, Prof. Patrik Johansson
ChemPhysChem, https://doi.org/10.1002/cphc.202000153. Read article.

Phosphines and N -Heterocycles Joining Forces: an Emerging Structural Motif in PNP-Pincer Chemistry

Phosphines and N -Heterocycles Joining Forces: an Emerging Structural Motif in PNP-Pincer Chemistry

Meridionally coordinating monoanionic PNP ligands that are based on a central N -heterocycle are particularly versatile ligand platforms, by their pincer complexes are known for nearly all the d-block metals. Such pincer complexes have found widespread application, for example in homogeneous catalysis. This emerging field of coordination chemistry is reviewed.

[Minireview]
Dr. Lukas S. Merz, Dr. Joachim Ballmann, Prof. Lutz H. Gade
European Journal of Inorganic Chemistry 2020, 2023. Read article.

Cyclic Aliphatic Hydrocarbons as Linkers in Metal-Organic Frameworks: New Frontiers for Ligand Design

Cyclic Aliphatic Hydrocarbons as Linkers in Metal-Organic Frameworks: New Frontiers for Ligand Design

Designer ligands for MOFs : This Minireview summarizes the recent developments in cyclic aliphatic ligand design for metal-organic frameworks (MOFs) from a ligand synthesis perspective, focusing on the cycloalkanes and fused polycyclic species adamantane, cubane and bicyclo[2.2.2]octane. Their benefit as three-dimensional building blocks, and the challenges and opportunities are explored where organic synthetic approaches can contribute to the development of bespoke microporous materials, with particular emphasis on their future possibilities in hydrophobic frameworks.

[Minireviews]
Valentyna D. Slyusarchuk, Prof. Paul E. Kruger, Dr. Chris S. Hawes
ChemPlusChem 2020, 85, 845. Read article.

Recent Advances in Microwave Assisted Multicomponent Reactions

Recent Advances in Microwave Assisted Multicomponent Reactions

Microwave assisted multicomponent reactions provide facile and expeditious procedures for the synthesis of several diversely functionalised molecules. The advancements in this field for the synthesis of acyclic, heterocyclic, fused heterocyclic etc. were described in the review. A comparison of microwave assisted and conventional methods are well discussed in the review. In addition, an idea on the effect of greener solvents, effect of catalysts etc. on microwave assisted MCR reactions also explored in the review.

[Reviews]
Jaleel Fairoosa, Salim Saranya, Sankaran Radhika, Prof. Dr. Gopinathan Anilkumar
ChemistrySelect 2020, 5, 5180. Read article.

Transportable Mononuclear Metal Atoms as Building Blocks for Bottom-up Material Fabrication: Pt1(0) and Au1(0) Atoms in Stock Solutions

Transportable Mononuclear Metal Atoms as Building Blocks for Bottom-up Material Fabrication: Pt1(0) and Au1(0) Atoms in Stock Solutions

In stock : Stock solutions of reduced mononuclear M1(0) (M=Pt, Au) atoms are prepared from their chloride salt precursors in removable solvent glycol ether/ethanol/H2O. Glycol ether and HCl function as strippable shields prevent M1(0) atoms from aggregation. The releasable M1(0) atoms suit as building-blocks for designable bottom-up material fabrications. Specifically, M1(0) atoms are readily transported onto the TiO2 surface and remain in the reduced mononuclear state.

[Full Papers]
Dr. Huixiang Li, Dr. Changhui Liang, Dr. Pan Gao, Prof. Guangjin Hou, Dr. Kairui Liu, Dr. Wei Liu, Dr. Qike Jiang, Prof. Shi Bai, Prof. Z. Conrad Zhang
ChemNanoMat, https://doi.org/10.1002/cnma.202000193. Read article.

Ligand Field Theory for Planar Complexes: First Principles Validation of the Critical Effects of Coordination Voids

Ligand Field Theory for Planar Complexes: First Principles Validation of the Critical Effects of Coordination Voids

The local ligand field potential in a cell containing a ligand is higher than the average that leads to positive parameter values and an increase in d orbital energies, but it is lower in a “coordination void” and the parameters are negative. Voids can exert strong σ and π effects. They also illustrate a fundamental difference between ligand field theory as originally envisioned by its pioneers and the simple MO overlap approach which has become the commonly accepted picture.

[Communications]
Prof. Dr. Robert J. Deeth
European Journal of Inorganic Chemistry 2020, 1960. Read article.

Leveraging Actinide Hydrolysis Chemistry for Targeted Th and U Separations using Amidoxime-Functionalized Poly(HIPE)s

Leveraging Actinide Hydrolysis Chemistry for Targeted Th and U Separations using Amidoxime-Functionalized Poly(HIPE)s

Amidoxime functionalized poly(high internal phase emulsions) are used for early actinide separations. The porous monoliths are found to have an unusual selectivity for Th versus U, achieving >90 % uptake in less than an hour. X-ray scattering data suggests the presence of Th clusters within the polymer.

[Articles]
Marek Piechowicz, Dr. Renato Chiarizia, Dr. S. Skanthakumar, Prof. Dr. Stuart J. Rowan, Dr. L. Soderholm
ChemPhysChem, https://doi.org/10.1002/cphc.202000155. Read article.

Insights into the Thermal and Photochemical Reaction Mechanisms of Azidoacetonitrile. Spectroscopic and MS-CASPT2 Calculations

Insights into the Thermal and Photochemical Reaction Mechanisms of Azidoacetonitrile. Spectroscopic and MS-CASPT2 Calculations

The first reaction step for both the thermal and photochemical processes gives N2 elimination and the closed-shell singlet nitrene derivative (11A′, NCH2CN). Then, HNCHCN and HNCHNC are formed by 1,2-H shift on the nitrene derivative. While the pyrolysis ends with the formation of HCN, the photochemical reaction yields the imine derivatives plus HCN and CNH, which (in a subsequent reaction) form adenine, as it was found by Boyer, Dunn and Kooi in 1975.

[Articles]
Dr. Manuel Algarra, Prof. Juan Soto
ChemPhysChem, https://doi.org/10.1002/cphc.202000201. Read article.

Oxidative Catalysis by TAMLs: Obtaining Rate Constants for Non-Absorbing Targets by UV-Vis Spectroscopy

Oxidative Catalysis by TAMLs: Obtaining Rate Constants for Non-Absorbing Targets by UV-Vis Spectroscopy

Need to measure rate constants k II′ of a catalytic reaction by UV/Vis spectroscopy but neither substrate, S1, nor product absorb light? Tetra-amido macrocyclic ligand (TAML) catalysis shows a solution and sends important practical messages.

[Communications]
Dr. Yogesh Somasundar, Iris C. Lu, Dr. Matthew R. Mills, Lisa Y. Qian, Ximena Olivares, Prof. Dr. Alexander D. Ryabov, Prof. Dr. Terrence J. Collins
ChemPhysChem, https://doi.org/10.1002/cphc.202000222. Read article.

A Critical Analysis about the Underestimated Role of the Electrolyte in Batteries Based on Organic Materials

A Critical Analysis about the Underestimated Role of the Electrolyte in Batteries Based on Organic Materials

The importance of the electrolyte : Redox active organic materials are currently considered as very interesting candidates for the realization of sustainable energy storage devices. This review aims to supply a critical overview about the work carried out so far on the development of electrolytes suitable for these materials.

[Minireviews]
Patrick Gerlach, Prof. Dr. Andrea Balducci
ChemElectroChem 2020, 7, 2364. Read article.

Constitution and Conductivity of Metalloporphyrin Tapes

Constitution and Conductivity of Metalloporphyrin Tapes

Porphyrin tapes: Oxidative chemical vapor deposition of 5,15-disubstituted metalloporphyrins gives metalloporphyrin tapes (M = 2H, FeIIICl, CoII, NiII, CuII, ZnII, PdII) in a single step. The metal center steers the regioselectivity of the initial C-C coupling reaction. The resulting double or triple linkages determine the NIR absorbance and conductivity of the resulting thin films.

[Full Papers]
Giuseppe Bengasi, Louise Quétu, Dr. Kamal Baba, Alexander Ost, Dr. João P. Cosas Fernandes, Patrick Grysan, Prof. Dr. Katja Heinze, Dr. Nicolas D. Boscher
European Journal of Inorganic Chemistry 2020, 1938. Read article.

Progressive Folding and Adaptive Multivalent Recognition of Alkyl Amines and Amino Acids in p -Sulfonatocalix[4]arene Hosts: Solid-State and Solution Studies

Progressive Folding and Adaptive Multivalent Recognition of Alkyl Amines and Amino Acids in p -Sulfonatocalix[4]arene Hosts: Solid-State and Solution Studies

Flexible guests : Molecular recognition of cationic 1,ω-diammonium-alkanes and 1,ω-amino-acids of variable lengths within p -sulfonatocalix[4]arene hosts sheds light on the constitutional adaptivity of flexible folded chains by maximizing multivalent contacts with the host receptor cavity. A comprehensive screening of 30 single-crystal structures allowed the accurate determination of the folded guest molecules structures under confinement.

[Full Papers]
Liya Dai, Dr. Wei-Xu Feng, Shao-Ping Zheng, Dr. Ji-Jun Jiang, Dr. Dawei Wang, Dr. Arie van der Lee, Dan Dumitrescu, Dr. Mihail Barboiu
ChemPlusChem, https://doi.org/10.1002/cplu.202000232. Read article.

Spray-Flame-Prepared LaCo1-x FexO3 Perovskite Nanoparticles as Active OER Catalysts: Influence of Fe Content and Low-Temperature Heating

Spray-Flame-Prepared LaCo1-x FexO3 Perovskite Nanoparticles as Active OER Catalysts: Influence of Fe Content and Low-Temperature Heating

Burn it up : Spray-flame-prepared LaCo1-x Fex O3 perovskite nanoparticles are catalytically active materials for the oxygen eVolution reaction (OER). The bulk and surface properties of catalysts prepared under different conditions are elucidated to explain their OER activity trends. The most active and stable catalysts possess a high content of oxygen deficient perovskite phase with low-coordinated surface oxygen atoms/surface oxygen vacancies while showing a highly crystalline surface structure.

[Articles]
Baris Alkan, Danea Medina, Joachim Landers, Markus Heidelmann, Ulrich Hagemann, Soma Salamon, Prof. Corina Andronescu, Prof. Heiko Wende, Prof. Christof Schulz, Prof. Wolfgang Schuhmann, Prof. Hartmut Wiggers
ChemElectroChem, https://doi.org/10.1002/celc.201902051. Read article.