The influence of the hydrophobic core on the equilibrium between a series of PdII/PtII-directed self-assembled metallacyles with their ring-in-ring complexes is reported in this work. It was possible to fine-tune the system response against external stimuli such as concentration, temperature (illustrated in the cover), polarity or addition of an aromatic guest. More information can be found in the Full Paper by V. Blanco, C. Peinador, M. D. García, et al. (DOI: 10.1002/chem.201902851).
[Cover Pictures]
Iago Neira, Dr. Cristina Alvariño, Dr. Olaya Domarco, Dr. Víctor Blanco, Prof. Carlos Peinador, Prof. Marcos D. García, Prof. José M. Quintela
doi.org/10.1002/chem.201904509
Let's tune it! The response against external stimuli of constitutionally dynamic systems formed by metallacyclic (en)M2L2 (M=PdII, PtII) species and ring-in-ring (en)M4L4 complexes, while keeping a general trend, can be tuned upon change of the hydrophobic core of a series of aryl-extended 4,4′-bipyridinium ligands (see figure).
[Full Papers]
Iago Neira, Dr. Cristina Alvariño, Dr. Olaya Domarco, Dr. Víctor Blanco, Prof. Carlos Peinador, Prof. Marcos D. García, Prof. José M. Quintela
doi.org/10.1002/chem.201902851
“Our story started 16 years ago, when Fabio Marchetti was a PhD student dealing with the synthesis and the reactivity of the first diiron vinyliminium compounds, easily available from Fe2Cp2(CO)4 in a few steps.” Read more about the story behind the cover in the Cover Profile and about the research itself on page ▪▪ ff. (DOI: 10.1002/chem.201902885).
[Cover Profile]
Dalila Rocco, Dr. Lucinda K. Batchelor, Dr. Gabriele Agonigi, Simona Braccini, Prof. Federica Chiellini, Silvia Schoch, Dr. Tarita Biver, Dr. Tiziana Funaioli, Prof. Stefano Zacchini, Dr. Lorenzo Biancalana, Marina Ruggeri, Prof. Guido Pampaloni, Prof. Paul J. Dyson, Prof. Fabio Marchetti
doi.org/10.1002/chem.201904317
Chemistry in water; new rules. Yep, take an old silyl hydroxyl protecting group like Ph2MeSi (DPMS), put the derived ether under either of two different aqueous conditions and “boom”; it can be removed selectively in the presence of TBS, TIPS, and TBDPS ethers under very mild conditions. The first: cat. RSO2F/EtOH (i. e., a SuFEx reagent) under micellar catalysis conditions. The second: 18-crown-6 (stoichiometric). That's it. Take your pick!
[Communications]
Nnamdi Akporji, Josh Lieberman, Michael Maser, Dr. Masahiko Yoshimura, Dr. Zarko Boskovic, Prof. Bruce H. Lipshutz
doi.org/10.1002/cctc.201901232
Synthesis, single-crystal X-ray structures and photophysical properties of unprecedented helicene containing 2,6-bis(pyrazolyl)pyridine ligands and corresponding ReI and RuII complexes are reported. Both the ligands and the RuII complexes show fluorescence properties in the violet and blue regions respectively, while the ReI complex exhibits strong phosphorescence at 77 K.
[Full Papers]
Alexandre Abhervé, Kévin Martin, Andreas Hauser, Narcis Avarvari
doi.org/10.1002/ejic.201900870
Make a PACT: A diazide complex, [Ru(η6-p-cymene)pta(N3)2] (pta: 1,3,5-triaza-7-phosphaadamantane), is inert in water, but slowly releases the azide ligand upon exposure to light. The in vitro cytotoxicity of the complex in the dark and upon light exposure in human cervical carcinoma and noncancerous retinal pigment epithelium cells is investigated.
[Full Papers]
Dr. Anna K. Renfrew, Johannes Karges, Dr. Rosario Scopelliti, Dr. Felix D. Bobbink, Prof. Dr. Patrycja Nowak-Sliwinska, Dr. Gilles Gasser, Prof. Dr. Paul J. Dyson
doi.org/10.1002/cbic.201900236
Protein-nucleotide contacts in a noncrystalline bacterial DnaB helicase sedimented in the NMR rotor were probed by 31P- and 1H-detected solid-state NMR spectroscopy. The sensitivity of 1H chemical shifts to hydrogen bonding was explored and used to identify residues involved in nucleotide coordination.
[Communications]
Dr. Thomas Wiegand, Maarten Schledorn, Alexander A. Malär, Riccardo Cadalbert, Alexander Däpp, Dr. Laurent Terradot, Prof. Dr. Beat H. Meier, Dr. Anja Böckmann
doi.org/10.1002/cbic.201900439
Diiron complexes with a bridging vinyliminium ligand show antiproliferative activity towards A2780 and A2780cisR cancer cell lines, and possess several ideal features for a drug, namely multi-gram scale synthesis, wide structural diversity, amphiphilicity, good stability in aqueous media and selectivity against cancerous cells compared to HEK-293 normal cells. More information can be found in the Full Paper by P. J. Dyson, F. Marchetti, et al. (DOI: 10.1002/chem.201902885).
[Cover Pictures]
Dalila Rocco, Dr. Lucinda K. Batchelor, Dr. Gabriele Agonigi, Simona Braccini, Prof. Federica Chiellini, Silvia Schoch, Dr. Tarita Biver, Dr. Tiziana Funaioli, Prof. Stefano Zacchini, Dr. Lorenzo Biancalana, Marina Ruggeri, Prof. Guido Pampaloni, Prof. Paul J. Dyson, Prof. Fabio Marchetti
doi.org/10.1002/chem.201904316
Mind the gap: A marked discontinuity in performances is observed with pyridine triazolylidene Ir-catalysts for water oxidation driven by CAN when passing from R=Me to R=Et substituents. Steric effects are likely responsible for the boost of activity observed for R≥Et.
[Full Papers]
Dr. Ilaria Corbucci, Dr. Francesco Zaccaria, Dr. Rachel Heath, Giordano Gatto, Prof. Cristiano Zuccaccia, Prof. Martin Albrecht, Prof. Alceo Macchioni
doi.org/10.1002/cctc.201901092
Folding native: Chaperones bind native client proteins on locally frustrated surfaces in a multiconformational ensemble. The ensemble of client structures interconverts under thermal equilibrium, while the client remains bound to the chaperone. The energy landscape of this interaction mode is broad and the large conformational entropy of the bound state adds favorably to the free energy of binding.
[Concepts]
Prof. Dr. Lichun He, Prof. Dr. Sebastian Hiller
doi.org/10.1002/cbic.201900215
Triazolylidene ligands with O-functionalized tethers comprising esters, ethers, and hydroxy groups have been coordinated to late transition metals. While the hydroxy group is strongly chelating in palladium(II) complexes, it is hemilabile in analogous iridium(I) and rhodium(I) systems.
[Full Papers]
René Pretorius, Ava McDonald, Ligia Regueira Beltrão da Costa, Helge Müller-Bunz, Martin Albrecht
doi.org/10.1002/ejic.201900724
Communication is key! We discuss the results of a multi-scale approach to probe the interplay between structural rearrangements of supported Pt nanoparticles for electrochemical oxygen reduction reaction and their catalytic activity.
[Articles]
Dr. Kevin Rossi, Dr. Gian Giacomo Asara, Dr. Francesca Baletto
doi.org/10.1002/cphc.201900564
Catalyst tuning: Iron aminophenolates: aziridination yields parallel the FeIII/II reduction potentials of the catalyst precursors allowing to evaluate the aziridination capacity of the catalyst by cyclic voltammetry experiments.
[Communications]
Dr. Guillaume Coin, Dr. Ranjan Patra, Dr. Martin Clémancey, Patrick Dubourdeaux, Dr. Jacques Pécaut, Colette Lebrun, Dr. Ludovic Castro, Dr. Pascale Maldivi, Dr. Sylvie Chardon-Noblat, Dr. Jean-Marc Latour
doi.org/10.1002/cctc.201901211
The power of two irons: Diiron vinyliminium complexes, easily available even in large scale, represent a new class of potential anticancer agents with multimodal action. These compounds offer a wide structural variability and possess appreciable solubility and good stability in aqueous solutions.
[Full Papers]
Dalila Rocco, Dr. Lucinda K. Batchelor, Dr. Gabriele Agonigi, Simona Braccini, Prof. Federica Chiellini, Silvia Schoch, Dr. Tarita Biver, Dr. Tiziana Funaioli, Prof. Stefano Zacchini, Dr. Lorenzo Biancalana, Marina Ruggeri, Prof. Guido Pampaloni, Prof. Paul J. Dyson, Prof. Fabio Marchetti
doi.org/10.1002/chem.201902885
The recently discovered photochemical reductive amination and the enantioselective amine synthesis by combined photoredox/enzymatic catalysis is reviewed.
[Minireview]
Xingwei Guo, Yasunori Okamoto, Mirjam R. Schreier, Thomas R. Ward, Oliver S. Wenger
doi.org/10.1002/ejoc.201900777
How did they get here? X-ray photoelectron spectroscopy of post-mortem Cu2O thin film electrodes characterized following an air-free transfer to ultra-high vacuum unveils their complete transformation into Cu0 in the course of CO2 electroreduction.
[Articles]
Dr. Anastasia A. Permyakova, Dr. Juan Herranz, Dr. Mario El Kazzi, Justus S. Diercks, Dr. Mauro Povia, Léa Rose Mangani, Michael Horisberger, Dr. Alexandra Pătru, Prof. Dr. Thomas J. Schmidt
doi.org/10.1002/cphc.201900468
Don't stop moving! A transaminase-mediated single-step process in continuous mode leads to excellent biogenic aldehyde yields (90-95 %), starting from the corresponding commercially available amines. Coimmobilization of the pyridoxal phosphate (PLP) cofactor eliminated the need for the exogenous addition of this reagent, without affecting the longevity of the system; thus delivering a truly self-sufficient process.
[Communications]
Dr. Martina L. Contente, Prof. Francesca Paradisi
doi.org/10.1002/cbic.201900356
Hot off the press: Conjugated coumarin-based oxime-esters as unimolecular photoinitiators can efficiently induce photopolymerization for two-photon three-dimensional printing.
[Communications]
Wanwan Qiu, Peng Hu, Junzhe Zhu, Prof. Dr. Ren Liu, Dr. Zhiquan Li, Zhiyong Hu, Prof. Dr. Qidai Chen, Dr. Kurt Dietliker, Prof. Dr. Robert Liska
doi.org/10.1002/cptc.201900164
Photoinduced charge-shift reactions and the possibility of light-driven charge accumulation were explored in a molecular triad comprising two donors and one photosensitizer.
[Full Papers]
Michael Skaisgirski, Christopher B. Larsen, Christoph Kerzig, Oliver S. Wenger
doi.org/10.1002/ejic.201900453
Testing durability fast: A “fit-for-purpose” protocol for accelerated durability investigations has been developed to test nickel oxyhydroxide (NiOx) based electrocatalysts for alkaline oxygen evolution reaction (OER). Electrochemical ageing of high-surface-area nickel (Raney Ni) has shown a competitive overpotential for the OER. Applying an advanced accelerated durability test evaluation, it is demonstrated that the active β system of Raney NiOx exhibits high stability at conditions suitable for photovoltaic applications. During 55 h no significant decay in performance is detected.
[Articles]
Dr. Dario Delgado, Francesco Bizzotto, Dr. Alessandro Zana, Prof. Dr. Matthias Arenz
doi.org/10.1002/cphc.201900195
The structure sensitivity of the oxygen evolution reaction is studied by combining electrochemistry, in situ spectroscopy, and density functional theory calculations.
[Articles]
Francesco Bizzotto, Dr. Hassan Ouhbi, Dr. Yongchun Fu, Dr. Gustav K. H. Wiberg, Prof. Dr. Ulrich Aschauer, Prof. Dr. Matthias Arenz
doi.org/10.1002/cphc.201900193
A novel and general protocol for the copper catalyzed reductive elimination of acyl azides to nitriles using triethoxysilane is reported. Various nitriles are obtained in moderate to excellent yields with good functional group tolerance and high chemoselectivity.
[Communications]
Prof. Yang Chen, Yu Liu, Xiao Zhang, Da Lu, Lixin Yang, Junfeng Deng, Prof. Shengqi Deng
doi.org/10.1002/slct.201802918
Carboxylic functionalized β-carbolines have been synthesized in good to excellent yields and high selectivity by oxygen in the presence of NHPI and transition metal salt under mild conditions
[Communications]
Hongda Qiu, Weida Liang, Dr. Gongjun Zhang, Miaoman Lin, Wanmin Liu, Prof. Zhanghua Gao, Dr. Wenting Wei, Dr. Chunlan Tang, Dr. Haixiao Jin, Prof. Hongze Liang, Prof. Xiaojun Yan
doi.org/10.1002/slct.201803007
Synthesis, characterization and complexation ability study of a series of Betti bases from 4-(3-pyridyl)azo-1-naphthol dye, possessing flexible methylene or more constrained aryl-methyne spaced NH-containing side-chains, is presented. An unexpected result with side-chain pyridyl group replacement was obtained and the product was analysed by XRD. A possible pathway was suggested and synthetically confirmed.
[Full Papers]
Prof. Dr. Vanya B. Kurteva, Dr. Lubomir A. Lubenov, Prof. Dr. Boris L. Shivachev, Prof. Dr. Rositsa P. Nikolova, Prof. Dr. Katharina M. Fromm
doi.org/10.1002/slct.201802745