Computational Insights into the Reaction Mechanisms of Nickel-Catalyzed Hydrofunctionalizations and Nickel-Dependent Enzymes

Computational Insights into the Reaction Mechanisms of Nickel‐Catalyzed Hydrofunctionalizations and Nickel‐Dependent Enzymes

In the nick-el of time: Developments in sustainability and applications of transition-metal catalysis have led to increasing interest in less toxic and inexpensive nickel catalysts. Computational insights into the reaction mechanisms of Ni-catalyzed hydrofunctionalizations and Ni-dependent enzymes have been presented. These studies reveal details of these transformations and thus assist in the development and design of sustainable catalysts. FG=functional group, MCR=multicomponent reaction.

[Focus Review]
Tonghuan Zhang, Xiaoyong Zhang, Lung Wa Chung
Asian J. Org. Chem., March 09, 2018, https://doi.org/10.1002/ajoc.201700645 Read article

Recent Progress in Chemistry of Multiple Helicenes

Recent Progress in Chemistry of Multiple Helicenes

Future for twists and turns: This review provides an overview of recent progress in multiple helicenes, which are an interesting class of nonplanar polycyclic aromatics with inherent multihelicity. Structures, stereochemical dynamics, synthesis through the Scholl reaction, and applications in organic electronics are discussed (see figure).

[Focus Review]
Changqing Li, Yong Yang, Qian Miao
Chem. Asian J., March 08, 2018, https://doi.org/10.1002/asia.201800073 Read article

Recent Advances in Supramolecular Gels and Catalysis

Recent Advances in Supramolecular Gels and Catalysis

Going soft: The correlation and advances in supramolecular gels and catalysis are reviewed. In addition to supramolecular catalysts and templates to access metal nanocomposites, the formation and potential applications of catalysis-triggered gels are also covered (see figure).

[Focus Review]
Weiwei Fang, Yang Zhang, Jiajie Wu, Cong Liu, Haibo Zhu, Tao Tu
Chem. Asian J., March 05, 2018, https://doi.org/10.1002/asia.201800017 Read article

Aromatic Aminocatalysis

Aromatic Aminocatalysis

Conjugation innovation: This Focus Review summarizes the advent and development of aromatic aminocatalysis in bioconjugation reactions and asymmetric catalysis, as well as in inert C−H/C−C-functionalization processes.

[Focus Review]
Jian Lv, Qi Zhang, Mao Cai, Yanfang Han, Sanzhong Luo
Chem. Asian J., March 01, 2018, https://doi.org/10.1002/asia.201701773 Read article

Energy Transfer in Dye-Coupled Lanthanide-Doped Nanoparticles: From Design to Application

Energy Transfer in Dye‐Coupled Lanthanide‐Doped Nanoparticles: From Design to Application

Breaking open the shell: Dye-coupled lanthanide-doped nanoparticles are promising materials for many emerging applications. Controlling energy transfer between the dye and nanoparticle is critical for achieving desired properties in the platform (see figure). This review discusses rational designs to incorporate functional dyes with lanthanide-doped nanoparticles. The applications of the platform in biomedicine and energy conversion are highlighted.

[Focus Review]
Juan Wang, Renren Deng
Chem. Asian J., February 27, 2018, https://doi.org/10.1002/asia.201701817 Read article

Amorphous Materials for Enhanced Localized Surface Plasmon Resonances

Amorphous Materials for Enhanced Localized Surface Plasmon Resonances

A light matter: The discovery of new plasmonic amorphous materials might offer new means of light–matter interactions, thus leading to exciting opportunities for their practical application (see figure). This review focuses on amorphous plasmonic materials and summarizes state-of-the art experiments on these materials for enhanced localized surface plasmon resonances.

[Focus Review]
Chuanhui Zhu, Qun Xu
Chem. Asian J., February 23, 2018, https://doi.org/10.1002/asia.201701722 Read article

Carbon Dots: Bottom-Up Syntheses, Properties, and Light-Harvesting Applications

Carbon Dots: Bottom‐Up Syntheses, Properties, and Light‐Harvesting Applications

On the dot: In this review, we summarize the recent progress in carbon dots synthesized from bottom-up approaches. The dots possess high absorption and charge-transfer abilities for light-harvesting applications (see figure).

[Focus Review]
Yuri Choi, Yeongkyu Choi, Oh-Hoon Kwon, Byeong-Su Kim
Chem. Asian J., February 21, 2018, https://doi.org/10.1002/asia.201701736 Read article

Catalytic Asymmetric Synthesis of α-Trifluoromethylated Carbinols: A Case Study of Tertiary Propargylic Alcohols

Catalytic Asymmetric Synthesis of α‐Trifluoromethylated Carbinols: A Case Study of Tertiary Propargylic Alcohols

Fluoro and fauna: The catalytic asymmetric synthesis of CF3-substituted tertiary propargylic alcohols is summarized, based on three retrosynthetic approaches, namely one trifluoromethylation approach and two building-block strategies.

[Focus Review]
Hidetoshi Noda, Naoya Kumagai, Masakatsu Shibasaki
Asian J. Org. Chem., February 21, 2018, https://doi.org/10.1002/ajoc.201800013 Read article

Integrating TEMPO and Its Analogues with Visible-Light Photocatalysis

Integrating TEMPO and Its Analogues with Visible‐Light Photocatalysis

Shedding light on TEMPO: By integrating 2,2,6,6-tetramethylpiperidine N-oxide (TEMPO) with photocatalysis, outstanding visible-light-induced selective organic transformations can be facilitated. TEMPO, or one of its analogues, acts as a coupling agent, a stoichiometric oxidant, or, in most cases, a co-catalyst with metal complexes, metal-free organic dyes, or semiconductors for visible-light photocatalysis.

[Focus Review]
Xianjun Lang, Jincai Zhao
Chem. Asian J., February 19, 2018, https://doi.org/10.1002/asia.201701765 Read article

Ruthenium-Catalyzed Aerobic Oxidation of Amines

Ruthenium‐Catalyzed Aerobic Oxidation of Amines

Transition-metal-catalyzed aerobic oxidations of amines remain at the core of fundamental organic reactions owing to the value-added products formed. Ruthenium, on the other hand, is widely utilized for various oxidative transformations. This review summarizes the specific use of ruthenium catalysts in aerobic oxidation of amines. Moreover, it focuses on the mechanistic detail in each case and challenges that still need to be addressed.

[Focus Review]
Ritwika Ray, Arijit Singha Hazari, Goutam Kumar Lahiri, Debabrata Maiti
Chem. Asian J., February 19, 2018, https://doi.org/10.1002/asia.201701748 Read article

Recent Developments and Perspectives in the Asymmetric Mannich Reaction

Recent Developments and Perspectives in the Asymmetric Mannich Reaction

Just another Mannich Monday: This Focus Review provides an overview of recent advances in the asymmetric Mannich reaction, including its scope, limitations, and applications.

[Focus Review]
Salim Saranya, Nissy Ann Harry, K. Keerthi Krishnan, Gopinathan Anilkumar
Asian J. Org. Chem., February 15, 2018, https://doi.org/10.1002/ajoc.201700679 Read article

Fundamental Understanding of Nanostructured Si Electrodes: Preparation and Characterization

Fundamental Understanding of Nanostructured Si Electrodes: Preparation and Characterization

Catch up Si: This focus review encapsulates targeted synthetic protocols and advanced characterization techniques for nanostructured Si anodes in lithium-ion batteries. From this retrospective and perspective viewpoints, it aims to offer a fundamental understanding of Si anodes and insights into how to approach next-generation designs for Si anodes.

[Focus Review]
Jaegeon Ryu, Taesoo Bok, Sungho Kim, Soojin Park
ChemNanoMat, February 08, 2018, https://doi.org/10.1002/cnma.201700362 Read article

Thia-Michael Addition: An Emerging Strategy in Organic Synthesis

Thia‐Michael Addition: An Emerging Strategy in Organic Synthesis

The road to addition: The advent of the thia-Michael addition reaction in organic synthesis and its ever-burgeoning applications in the fields of medicinal chemistry, catalysis, drug discovery, and materials science has been a profound scientific development. This Focus Review plots the journey of the thia-Michael addition reaction in organic synthesis, and is categorized according to catalyzed and catalyst-free thia-Michael addition reaction.

[Focus Review]
Preeti Wadhwa, Anupreet Kharbanda, Anuj Sharma
Asian J. Org. Chem., February 08, 2018, https://doi.org/10.1002/ajoc.201700609 Read article

Vicinal anti-Dioxygenation of Alkenes

Vicinal anti‐Dioxygenation of Alkenes

Known for being choosy: A cornerstone reaction in organic synthesis, the vicinal anti-dioxygenation of simple alkenes provides a direct access to 1,2-diols and their derivatives. In this Focus Review, the advances in this research area are surveyed and organized according to the type of the reaction pathway.

[Focus Review]
Chuan Wang
Asian J. Org. Chem., February 05, 2018, https://doi.org/10.1002/ajoc.201700621 Read article

Synthesis and Chemical Transformations of Fluorosulfates

Synthesis and Chemical Transformations of Fluorosulfates

S−F 49ers: Methods for the synthesis of fluorosulfates from the reactions of phenols and alcohols with sulfuryl fluoride, fluorosulfonic acid, sulfuryl chloride fluoride, and fluorosulfonic anhydride are summarized. The broad application of fluorosulfates in synthetic transformations, which include catalyzed amination, cross-coupling, sulfur(VI) fluoride exchange, carbonylation, hydrolysis, and alcoholysis, are also discussed.

[Focus Review]
Lekkala Revathi, Lekkala Ravindar, Jing Leng, Kadalipura Puttaswamy Rakesh, Hua-Li Qin
Asian J. Org. Chem., January 31, 2018, https://doi.org/10.1002/ajoc.201700591 Read article

The Liebeskind–Srogl Cross-Coupling Reaction and its Synthetic Applications

The Liebeskind–Srogl Cross‐Coupling Reaction and its Synthetic Applications

In the cross-fire: This Focus Review highlights recent advances in the Liebeskind–Srogl cross-coupling reaction of a wide variety of organosulfur compounds with different organometallic reagents, and its applications in organic synthesis.

[Focus Review]
Hong-Gang Cheng, Han Chen, Yue Liu, Qianghui Zhou
Asian J. Org. Chem., January 26, 2018, https://doi.org/10.1002/ajoc.201700651 Read article